(Source: Endocrineweb News, USA)
MontclairA team of Baylor College of Medicine researchers may have identified a genetic therapy that can stimulate the growth of new insulin-producing pancreatic cells and reverse the symptoms of type 1 diabetes, according to a recent presentation at the Annual Meeting of the Endocrine Society.
In testing on mice, the investigation team showed that it is possible to stimulate the activity of the neurogenin3 gene, which instructs newly formed pancreatic cells to differentiate into insulin-producing beta cells. This solves one of the greatest challenges in treating type 1 diabetes. Individuals with the condition generally do not have enough beta cells, therefore they constantly have dangerously low levels of insulin.
However, creating more beta cells alone does not cure the condition. The reason why type 1 diabetics do not have adequate supplies of beta cells is usually because their body's own immune system attacks and destroys these cells. To combat this problem, the researchers turned to further genetic treatment. Read more
MontclairA team of Baylor College of Medicine researchers may have identified a genetic therapy that can stimulate the growth of new insulin-producing pancreatic cells and reverse the symptoms of type 1 diabetes, according to a recent presentation at the Annual Meeting of the Endocrine Society.
In testing on mice, the investigation team showed that it is possible to stimulate the activity of the neurogenin3 gene, which instructs newly formed pancreatic cells to differentiate into insulin-producing beta cells. This solves one of the greatest challenges in treating type 1 diabetes. Individuals with the condition generally do not have enough beta cells, therefore they constantly have dangerously low levels of insulin.
However, creating more beta cells alone does not cure the condition. The reason why type 1 diabetics do not have adequate supplies of beta cells is usually because their body's own immune system attacks and destroys these cells. To combat this problem, the researchers turned to further genetic treatment. Read more
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